In a healthcare system, the responsibility for patient’s safety is on the nurses, administrators, researcher, and physicians. They make sure that the patient handled safely and he/she is not prone to any system health care flaw. This perspective of patient health care safety linked with quality healthcare management. The role of nurses, physicians, and healthcare agencies are pivotal in addressing patient’s safety. The development of safety culture and its implementation for patient safety and care is also an integral part. The transmission of disease occurs through errors in preventive measures. It can eradicate through the proper application of preventive protocols.According to American nurses association, the patient safety linked to the Clean environment provided to the patient. The Institute of medicine defined the patient safety as the avoidance of injuries or any harm to the patient from the caring procedures. The healthcare procedures that are intended to help them may also injure if some errors happen. The only solution is to get rid of any failure by following the proper operating procedure to minimize the possibility of any mistake. (Ballard, K.A, 2003)The role of nurses, physicians and agencies are worth discussing in the implementation of quality care leading to the patient’s safety. The American Association of nurses addressed in the testimony to the Institute of medicine that the nurses are the main pillars of assurance of safety. If nurses stressed and fatigued, they would not pay their role efficiently as they will have a loop in their thinking process, would be more prone to accidental injuries while operational procedures, medications errors would also increase. The safety of patients depends on the working environment and nurses safety both. Nurses must be competent learners and critical thinkers to analyze and assess the condition of the patient and respond accordingly. They should opt for educational programs and train to get clinical practice. Certification of nurses in their respective fields would aid the proficiency in the execution of quality care to the patient.The development of safety culture is the fundamental pillar on which prevention of errors and harms to the patient can enforce. The organizations should report about any challenging flaw in the system with trust and work in potential to remove the error. The safety culture should have these elements such as open communication, feedback about the safety, training and competency opportunities, adequate trained staff to work, teamwork among all the employees. (Manneli, H.A & Woten, M.B, 2017)Sharp injuries from sharp objects such as needles; lancelets carry the chance of infectious diseases transmission such as HIV, Hepatitis. The nurses must train to practice sharp safety devices for the preventive measures form sharp object. The use of retractable needles, blunt suture needles, and needleless safety device in the form of IV system are the safety measures for the reduction of injury risk the incidence of the blood-borne infectious disease reported in U.K the illnesses reported were hepatitis through occupational injuries. (Caple C & Schub E.B, 2016)The development of joint commission for the patient’ safety happened in 2002. They reported healthcare-associated infection cases in 2, 039 hospitals in 2010 with the contribution of national healthcare safety network. TJC identified the causative agent to be the pathogen of Methicillin-resistant Staphylococcus bacteria. They identified the agent and provided measures for the prevention. The agent reservoir is patient, and transmission can reduce through no physical contact, knowledge to the families of the patient about transmission and education to the staff members about it, and use of antimicrobial agents in the working environment for the safety and avoidance of disease transmission. (Woten M, 2016)The onset of mucous malignancy referred to Kaposi’s sarcoma transmit through saliva. It occurs in immune suppressed patients. The adverse form is iatrogenic form. The transmission is through organ and blood transfusion. The prevention strategy should include adequate knowledge about the compatibility before blood transfusion or organ transplant, the implementation of a united network of organ sharing protocols should maintain in the hospitals. (Matteucci R.M & Caple C.M, 2016)The patient safety managed by trained employees including nurses, physicians, and healthcare agencies. Healthcare flaws are inevitable. They can happen anywhere anytime, the onlyNeed to consider is to follow proper medical protocol during operational procedures, education, and training of personnel about the disease transmission and to follow the guidelines for the avoidance of pathogenic disease.ReferencesBallard, K.A. (2003). Patient Safety: A Shared Responsibility. Online Journal of Issues in Nursing, 105-118.Caple C & Schub E.B. (2016). Sharps Injuries: Prevention — Using Safety Devices. CINAHL Nursing Guide.Manneli, H.A & Woten, M.B. (2017). Risk Management: Creating a Culture of Safety. CINAHL.Matteucci R.M & Caple C.M. (2016). Kaposi’s Sarcoma, Iatrogenic: Blood and Organ Safety. CINAHL Nursing Guide.Woten M, (2016). National Patient Safety Goals (The Joint Commission, 2016): Risk Assessment for MRSA Acquisition and Transmission. CINAHL Nursing Guide.